Friday, March 2, 2007

Tools of the Trade - More Potent than Tamiflu

Oseltamivir is an antiviral drug that is used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B. Like zanamivir, oseltamivir is a neuraminidase inhibitor. It acts as a transition-state analogue inhibitor of influenza neuraminidase, preventing new viruses from emerging from infected cells.

Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by Gilead Sciences and is currently marketed by Hoffmann-La Roche (Roche) under the trade name Tamiflu. It is generally available by prescription only.

With increasing fears about the potential for a new influenza pandemic, oseltamivir has received substantial media attention. Production capacity is limited, and governments (and even some private individuals) are stockpiling the drug.

On with the tools...

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1) On Feb 28th, FileZila 2.2.31 was released. FileZilla is a fast and reliable FTP client for windows with lots of useful features and an intuitive interface. Check out the change log for all the details.

2) On Feb 26th, Paint.NET 3.0.1 was released.

3) On Feb 25th, Oxid.it released Cain & Abel 4.5

New features:

  • WEP cracking speed up via wireless ARP requests injection (AirPcap USB adapter is needed).This feature has been successfully tested with Airpcap drivers v2.0 beta TX.
  • Ability to deauthenticate client stations from Access Points.
  • Added Windows Vista compatibility in NTLM Hashes Dumper, LSA Hashes Dumper and Syskey Dumper for hive files.
4) On Feb 23th, OpenSSL version 0.9.8e and 0.9.7m were released. Check out the change log. These releases include several important bugfixes.

5) On Feb 16th, Bart Puype released WGET 1.10.2 for Windows. This version is compiled with MS Visual C++ and linked with OpenSSL 0.9.7i.

6) On Jan 24th, Simon Tatham released Putty 0.59. PuTTY is a free implementation of Telnet and SSH for Win32 and Unix platforms, along with an xterm terminal emulator. Check out the change log for all the details.

7) In other news, Nullsoft has released Winamp 5.33. Check out the change log.

8) In beta news, WinRAR 3.70 Beta 4 is out. Check out the change log for the details

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